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Certain supplements, like licorice root and St
In line with this finding, PCTX upregulated CXCL1 in a time-dependent manner in myelinated A and C fibers but not in satellite glial cells, and the intrathecal injection of neutralizing antibodies against CX3CL1 or CX3CR1 and the macrophage toxin significantly reduced macrophage infiltration and delayed hypersensitivity induced by PCTX (Huang et al., 2014)
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Also, LPS activates TNF- to interact with its cognate receptor, causing activation of the nuclear factor-kappa B pathway with the induction of inflammatory and anti-apoptotic genes
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