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Individuals at increased risk of selenium deficiency Selenium deficiency has been reported in chronically ill patients who received total parenteral nutrition (TPN) without added selenium for prolonged periods of time

Studies have shown that knocking down the NNMT gene leads to increased expenditure of energy in adipocytes (Xu et al., 2022)
[DOI] [Google Scholar] Lismont C, Revenco I, Fransen M

This conservative initial dose allows assessment of individual tolerance and minimizes gastrointestinal side effects

[DOI] [PMC free article] [PubMed] [Google Scholar] 48.Morimoto S., Ichihara A