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Potential side effects Possible side effects of supplementary l-carnitine include, but are not limited to: Gut disturbance: l-carnitine does not have an established upper intake level, although doses above 3g per day may cause nausea, vomiting, abdominal cramps and diarrhoea Coronary artery disease: some research suggests l-carnitine may be linked to an increased risk of coronary artery disease and heart failure, especially in men and those who eat meat

Analysis of the microbiome: advantages of whole genome shotgun versus 16S amplicon sequencing

Whilst Lcarnitine is absorbed efficiently at physiological levels (with only 4% of tracer labelled Lcarnitine detected in the faeces of healthy adults eating a normal diet), pharmacokinetic studies of larger doses (26 g) of Lcarnitine in healthy volunteers consistently show poor oral bioavailability of 518%

doi: 10.1080/19490976.2023.2229569 15 ChenL.YangH.LiH.HeC.YangL.LvG

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