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We then performed a gene set enrichment analysis (GSEA) to determine the association between the expression of ACTL6A and signaling pathways in the RNA array results, which indicated significant differences between ACTL6A-KD cells and control cells in multiple metabolism-related pathways, among which GSH metabolism ranked as one of the most highly correlated pathways (Fig

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AKR1B1 is also involved in the synthesis of prostaglandins by catalyzing the conversion of PGH2 to prostaglandin F2alpha (PGF2)

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And puerarin is the most bioactive and abundant isoflavone compound in pueraria root, and the content of puerarin accounted for at least 2.4% of puerarin dried product [270] (Fig

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