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Most people tolerate collagen extremely well, but a small percentage of users report mild digestive issues, including acid reflux or a "heavy" feeling in the stomach

Biochemistry 38:929935 Brooks PJ, Theruvathu JA (2006) Acetaldehyde-DNA adducts: implications for the molecular mechanism of alcohol related carcinogenesis

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Pyruvate metabolism controls chromatin remodeling during CD4(+) T cell activation