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Together, these actions are thought to produce more pronounced weight loss and metabolic improvements than dual or single receptor agonists

METALLURGY C07ORGANIC CHEMISTRY C07DHETEROCYCLIC COMPOUNDS C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms CCHEMISTRY

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Hoffman DR, Cornatzer WE, Duerre JA (1979) Relationship between tissue levels of S-adenosylmethionine, S-adenosylhomocysteine, and transmethylation reactions