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The HGD gene is located on chromosome 3q13.33 and is composed of 16 exons that encode a protein of 445 amino acids

Haines, R

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As expected, T cell-independent (TI) type II immunization with TNP-Ficoll to evaluate MZB-dependent antigen binding and early antibody production 86,87,88 confirmed the deficit of MZB in Gclc fl/fl Mb1-Cre + mice (Supplementary Fig

Thus, changes in the GSH/GSSG ratio are fundamental in the fine-tuning of signal transduction, even under mild oxidative stress that underlies physiological events such as cell cycle regulation and other cellular processes (Schafer and Buettner, 2001)