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Data availability All data generated and analysed during this study are included in this published article and its Supplementary information file

Molecular Docking and Peptides Synthesis The X-ray crystal structure of Agaricus bisporus tyrosinase (2Y9W) was downloaded from the Protein Data Bank ( ( Cell Culture B16F10 cells were kept in Dulbecco's modified eagle medium supplemented with 10% heat-inactivated fetal bovine serum, and cells were cultured at 37C in an atmosphere with 5% CO 2

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Mutations in KRAS lead to the upregulation of the expression of the SLC7A5, SLC38A2, and SLC25A22 transporters in cancer cells, thereby promoting glutamine uptake [50]