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(20) Intestinal problems: Because B12 is absorbed in the intestines, any disease that impairs intestinal function can interfere with B12 absorption

Concurrent administration of pyridoxine with these medications has been reported to lower their therapeutic levels, so monitoring and dosage adjustments of the anticonvulsant might be required if high-dose vitamin B is given

Tim Lars Apr 29, 2024 at 8:54 AM

Depending on your outcomes and how well you tolerate the medication, your prescriber may recommend you move up to 2ml per week, or 1ml twice per week

I have been on metformin since I was diagnosed with diabetes several years ago