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The most important definition concerns acute damage caused by excessive and sudden pressure on the muscles, most often during physical exertion
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B12 may decrease ectopic nerve firing, which could explain why it helps alleviate painful symptoms [14]

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10.1126/science.451610 Science Summary Keywords opioid, synaptic plasticity, receptor signal transduction, neurotransmission, glutamate, GABA Citation Reeves KC, Shah N, Muoz B and Atwood BK (2022) Opioid Receptor-Mediated Regulation of Neurotransmission in the Brain
