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Acute insulin sensitivity changes also contribute

After the radical recognition, the detoxification of OH by GSH can take place, the OH is forwarded to CYS.SG and abstracts a hydrogen from this group

Recent work has established that the heterogenous nuclear ribonucleoprotein hnRNPA2/B1, a ubiquitous RNA binding protein involved in RNA processing, is a negative regulator of ATP7A expression and has implicated this RNA binding protein in the developmental expression of ATP7A (McCann, Hasan, et al., 2022)
doi: 10.1038/s41598-020-61458-5 139 PangC.ZhengZ.ShiL.ShengY.WeiH.WangZ.et al

ROS can oxidize methionine residues in proteins to form sulfoxides that can be reduced by MSR [150]
