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melanotic mcacule Labial Macules: Dark Spots on the Lip Melanotic macule - MEDizzy
Description
[PubMed: 17121837] 110
Neuroendocrine Factors It is also possible that a circulating factor (or factors) released by the brain in response to activation of the CNS leptin-melanocortin pathway may contribute to the cardioprotective actions of leptin

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The US Food and Drug Administration recently approved a phase II clinical trial of afamelanotide (SCENESSE, Clinuvel Pharmacueticals Ltd) combined with narrowband UV-B therapy for the treatment of vitiligo.4 We report the case of a 25-year-old man who came to our department for the sudden eruption of multiple melanocytic nevi and rapid transformation of existing nevi