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One group was given a diet supplemented with L-carnitine while another group received a diet without supplemental L-carnitine

In DKD kidney biopsy samples, long-chain acylcarnitines correlate with renal tubular lipotoxicity, mitochondrial dysfunction, and cell death


doi: 10.1016/j.clinbiochem.2010.02.005 98 ZouXJiangZLiLHuangZ

Nitric oxide is the endothelial factor responsible for relaxation of smooth musculature surrounding the arterials and the pre-capillary sphincters thereby producing vasodilation and increased blood flow into the capillary bed of the exercising muscle tissue