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10.1016/j.ejps.2022.106324 279 VermaasJ

Dysregulated glutarylation has been associated with pathological states, including inherited metabolic disorders like glutaric acidemia type I, neurodegenerative diseases, and cancer

As well as acting as a preventative measure, we now know that supplementation with glutathione can help patients infected with the virus and Glutathione has also shown some efficacy in the treatment of those who have a current COVID-19 infection (3)

Changes in the tumor microenvironment Extracellular matrix remodeling The effects of the extracellular matrix (ECM) on cells are primarily mediated by integrins, a family of cell surface receptors that attach cells to the matrix and trigger signal transduction [117]

104 For example, venlafaxine-loaded alginate nanoparticles showed superior targeting efficiency and behavioral outcomes in depression models compared to the same drug administered in solution form