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Rev Bras Cir Cardiovasc 2015

These observations underscore the involvement of the hypoxic microenvironment in MS-associated vascular pathology, implying that strategies aimed at improving vascular oxygenation, mitigating immunoinflammatory damage, downregulating vasoactive substances, and reversing vascular abnormalities may reduce ischemic damage to the skin and visceral organs

Metformin upregulates mitophagy in patients with T2DM: a randomized placebo-controlled study

Chun S, An J, Kim MS

10.1007/s12016-011-8285-8 6
