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These side effects commonly include/manifest as: Vomiting Diarrhoea Nausea Headache Weakness Tiredness Tingling sensation or numbness in your extremities Skin conditions like rosacea, acne, atopic dermatitis, and vitiligo Increased risk of colon cancer in older adults Vitamin B12 overdose increases your chances of hospitalisation and death in certain cases Less effective chemotherapy given for the treatment of cancer Side Effects of Overdose of Vitamin B12: Shots Vitamin B12 supplements are also delivered as high-dose shots directly into your system thereby reducing its deficiency quickly

IGFBP-1 regulates glucose levels through its effect on free IGF-1