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Muscularis macrophages establish cell-to-cell contacts with telocytes/PDGFR-positive cells and smooth muscle cells in the human and mouse gastrointestinal tract

doi: 10.1007/s00018-016-2190-5 114 ShiFLYuanLSWongTSLiQLiYPXuRet al

LC and CFS are excellent models for the gut-brain axis

This initiates a cascade of intracellular signaling reactions leading to molecular, cellular, and interstitial alterations, which manifest clinically as changes in the size, shape, and function of the heart
It helps to lower blood sugar levels, slow down gastric emptying, and reduce appetite