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2) Short-term aerobic exercise increases the number of monocytes, neutrophils, and lymphocytes (Alawna et al., 2020), while long-term exercise intervention suppresses the excessive activation of pro-inflammatory M1 macrophages and promotes the proportion of anti-inflammatory M2 macrophages, thus improving chronic low-grade inflammation (Sleijser-Koehorst et al., 2023

In Warren MJ, Smith (eds.)

Pale or yellow skin A lack of B12 can limit the production of red blood cells, which may cause the skin to look pale or have a hint of yellow

Organic acids (urine) Markers of malabsorption and bacterial/yeast dysbiosis - metabolites produced by the gastrointestinal microbiome Cellular energy and mitochondrial metabolites - biomarkers of carbohydrate and fatty acid metabolism, as well as the citric acid cycle (Creba) Neurotransmitter metabolites - by-products of the metabolism of epinephrine, norepinephrine, serotonin and dopamine Vitamin markers - specific indicators used to assess the functional levels of vitamin cofactors Toxin and detoxification markers refer to specific toxic metabolites and the body's ability to detoxify Oxalate markers are associated with kidney stone formation, oxidative stress and metabolic dysfunction

doi: 10.1146/annurev.bi.52.070183.003431
