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245 , G443G462 (1983)

A major functional axis linking microbiota to metabolic regulation is the production of short-chain fatty acids (SCFAs)acetate, propionate, butyrate, and lactatevia anaerobic fermentation of dietary fiber

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In addition, inflammation, excessive production of reactive oxygen species (ROS) and endoplasmic reticulum stress (ERS) in IPF lungs lead to repetitive damage to epithelial cells (Ornatowski et al., 2020)

Of note, B cell numbers were found to be reduced in PD patients (96, 101), along with an increase in IgA levels (102) that correlated with non-motor symptoms (96)