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P., Motta, M., Mistretta, A., Rampello, L., and Pennisi, G

Simo, R

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The liver macrophages and apoptotic or injured hepatocytes play a critical role in hepatic fibrogenesis by releasing several cytokines and growth factors (Lech and Anders, 2013

This pathway primarily occurs in the liver and kidney and involves four key enzymes: Trimethyllysine Hydroxylase (TMLH), Hydroxytrimethyllysine Aldolase (HTMLA), Trimethylaminobutyraldehyde Dehydrogenase (TMABA-DH), and -Butyrobetaine Hydroxylase (BBOX)
