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In addition, when cyanocobalamin is metabolized it will form cyanide which must be eliminated by the body

Some uncommon side effects that could occur are some weakness, nausea, bowel problems, dizziness, lethargy, weight loss, thirst, nervous irritability, itchy skin, frequent urination, high levels of calcium

A recent systematic review and meta-analysis of 21 randomized, placebo-controlled trials examining the effect of B-vitamin supplementation found the supplementation decreased homocysteine concentrations and improved measures global cognitive function but had no effect on individual measures of executive function, information processing speed, or episodic memory (89)