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ACC is inhibited through phosphorylation by AMPK, and ACCs inhibiting effect on CPT1A is relieved by lowering the malonyl-CoA level (Yao et al., 2020)

This sophisticated relationship, which incorporates alteration in the lipid, TG, cholesterol metabolism, IR, inflammation and oxidative stress, and the dysfunction of the hepatic hormone, is by some degree shaped by THs (Figure 1)

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Similarly, quercetin participates in the mitochondrial apoptotic pathway through Bcl-2-regulated ER stress while concurrently activating cytoprotective autophagy in human ovarian cancer cells (Liu et al., 2023)

Regular L-Carnitine primarily supports fat metabolism and physical performance