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The practical focus is glucose, kidney function, lipids, GI tolerance, gallbladder/pancreas symptoms, and thyroid-history cautions

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In their report from 2003 Voedingsnormen: vitamine B6, foliumzuur en vitamine B12 the council joined expert commissions from the American Institute of Medicine and the Scientific Committee for Human Food from the European Union, who had already reported 3 years earlier that toxicity from high dose vitamin B12 poses no real danger

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The good news is that B12 is one of the safest vitamins, but there are a few things to know about high-dose supplements and when theyre actually necessary