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References: Pizzorno J

Plant-based natural compounds as novel therapeutic avenues against tuberculosis: Emphasis on curcuminMicrobial Pathogenesis | September 2025 This study is done to review and screen various natural compounds from plant origin for anti-tubercular activity and focuses on curcumin due to its multi-target mechanism of action, potent anti-inflammatory and immune-modulatory effects, and its future potential has been addressed

Previously, Ccnd1Cdk4 cytoplasmic activity has been associated with the regulation of cell motility and invasion through the interaction with membrane-associated proteins, such as Filamin A, Ral GTPases and Paxillin [6, 8, 9, 49]

GI events (nausea, vomiting, diarrhea) were the dominant safety signal and occurred at rates higher than reported for Phase 2 retatrutide and higher than for comparable dual or mono-agonist trials

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