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Patients with acne should be advised accordingly

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2006 Mar;53(3):278-86

Exogenous ketone supplements, particularly ketone esters and HB, promote this metabolic shift by elevating circulating ketone levels and reducing reliance on glucose metabolism

It is diagnosed according to the Canadian consensus criteria, at least 6 months after onset when the following symptoms are present: fatigue, post-exertional malaise with a recovery period of at least 24 h, sleep dysfunction, pain, at least two neurological/neurocognitive symptoms and at least two symptoms involving the autonomic, neuroendocrine or immune system [19]