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Describing sub-1 mg retatrutide as a recomposition base or metabolic optimizer is therefore a mechanistic hypothesis, not an established clinical use

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The increased glucose (25 mM) was used to inhibit -cell glucagon secretion to diminish glucagon levels to basal levels to improve the dynamic range of the assay and thus effectively unmask the role of ligand-mediated glucagon secretion as described earlier 45

Bonnet A-L, Aboishava L, Mannstadt M

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