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Sun et al, 2010)
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10.31083/j.fbl2703105 264 ShaughnessyK
Up to 20% of cases of fALS is due to a mutation of the gene that encodes the enzyme Cu-Zn superoxide dismutase (SOD1)
Increased oxidative stress causes vascular dysfunction, NO deregulation, peripheral vascular resistance, increased blood pressure, and aldosterone-induced hypertension
