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doi: 10.1186/s12985-022-01814-1
Chemical stimulation of the intracranial dura induces enhanced responses to facial stimulation in brain stem trigeminal neurons
Cognitive Enhancement (Nootropic Properties): Semax may enhance memory and learning by upregulating brain-derived neurotrophic factor (BDNF) signaling in the hippocampus through the BDNF/TrkB pathway, which plays a key role in synaptic plasticity and long-term memory formation
Its efficacy and tolerability is currently being evaluated in a phase 3 trial [77] (Table 2 )
