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Do not do within 24 to 48 hours: - Direct sun exposure for 48 to 72 hours (mineral SPF if you must go outside) - Heavy exercise or sweating for 24 to 48 hours - Makeup for 12 to 24 hours Safe to apply immediately after needling: GHK-Cu serum (0.05%), plain hyaluronic acid, and mineral sunscreen

Scientific Insights: NSAIDs and Glutathione Depletion While NSAIDs are effective for managing pain and inflammation, studies suggest that they may contribute to glutathione depletion, particularly in the liver, where detoxification processes are heavily reliant on this antioxidant

Studies show that PSPE improves the antioxidant enzyme activity in C

10.1186/s12906-019-2463-2 283 TaubertD.BerkelsR.KlausW.RoesenR

10.1080/15376516.2023.2196687 Toxicol