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Description
J Neurochem 115: 1466-1477

an antibody that specifically binds to an EphA2 polypeptide comprises an amino acid sequence of one or more VL CDRs that are at least 35%, preferably at least 40%, at least 45%, at least 50%, at least 55%, at least 60%, at least 65%, at least 70%, at least 75%, at least 80%, at least 85%, at least 90%, at least 95%, or at least 99% identical to any of the VL CDRs listed in Table 2 or 3, supra

In addition to decreased ATP production, mitochondria can also release apoptotic factors under the influence of ROS such as cytochrome c and apoptosis-inducing factor

Mechanisms of chemotherapy-induced peripheral neuropathy

Esto es especialmente importante en el cerebro, que tiene grandes demandas de energa y es vulnerable al dao oxidativo