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Description
TBI is heterogeneous and varies widely in severity, clinical presentation, and pathophysiology (Ng and Lee, 2019)
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ATM-CHEK2: Ataxia telangiectasia mutated serine-checkpoint kinase 2
While an acute pharmacological dose of NAM can be converted by CYP2E1 to nicotinamide N-oxide, which is then excreted to the urine
doi: 10.1093/brain/122.8.1437
