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Barbacid, M

Oncol Lett (2018) 15(2):20106

The question of timing is one of the most common things we hear from our community

Witkowski, J

Increased ROS also activate STAT1 triggering the inflammatory process in the cochlea (Kaur et al., 2011), and the binding of inflammatory cytokines to their receptors further leads to an increase in ROS production in OHC cells.ROS and inflammatory responses reinforce each other, forming a positive feedback loop that further exacerbates OHC damage (See Figure 3)
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