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Immunofluorescence staining similarly revealed that the expression of PHB2, BECN1, and LC3 was significantly decreased in HG of the aged mice compared to HG of the young mice (Fig

As of the present moment, there are no published studies that have investigated the impact of melatonin on A burden specifically in humans

It was only recognized in the late 1980s that desensitization of insulin secretion, which describes a state of decreased secretory responsiveness of -cell to the glucose stimuli, is a pathophysiological phenomenon of -cell function and not just an in vitro artifact 30

These alternative splice variants have been raised due to the loss or gain of exons or introns, such as OsDJ-1C .1 losses one exon to generate OsDJ-1C .2 and loss of another exon make the second variant OsDJ-1C .3 (Figure S1)

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