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Description
Mechanism of PRP in Osteoarthritis PRP contains growth factors and cytokines that promote cartilage repair and modulate inflammation, including: Platelet-derived growth factor (PDGF): Stimulates chondrocyte proliferation and matrix synthesis Transforming growth factor-beta (TGF-): Encourages cartilage regeneration and reduces catabolic activity Vascular endothelial growth factor (VEGF): Enhances microcirculation to support healing Interleukin-1 receptor antagonist (IL-1Ra): Suppresses pro-inflammatory cytokines that degrade cartilage These biological effects differentiate PRP from corticosteroids , which primarily suppress symptoms but accelerate cartilage degradation with repeated use (PMID: 30404447)

doi: 10.1093/ajcn/nqab193
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Keep reconstituted GHK-Cu refrigerated at 2-8 degrees Celsius with a maximum use period of 30 days

If you rely on B12 shots prescribed by a doctor, please dont stop treatment, even if theyre painful due to a water-based solution or intramuscular delivery
