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Food and Function 10 (12), 77557766

Van Citters GW, Lin HC

S12), it was found that the combination of Zn 2+ , Cu 2+ and Qu (ZCQ) caused changes in more than 30 pathways, including the steroid biosynthesis pathway related to DHT [[48], [49], [50]], the TNF pathway related to inflammation [51], the TGF- pathway related to hair follicle growth cycle [52], the VEGF and HIF-1 pathways related to angiogenesis [53,54], and the AMPK pathway related to skin regeneration [55]

This occurs because the underlying biological drivers of obesity, hormonal setpoints, metabolic adaptation, and appetite regulation, reassert themselves once the pharmacological intervention is removed

Men in trials also reported sustained improvements in energy levels and reduced joint pain as excess weight came off