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Shishmanova-Doseva M, Atanasova D, Ioanidu L, Uzunova Y, Atanasova M, Peychev L, Tchekalarova J (2022) The anticonvulsant effect of chronic treatment with topiramate after pilocarpine-induced status epilepticus is accompanied by a suppression of comorbid behavioral impairments and robust neuroprotection in limbic regions in rats

Introduction Schizophrenia is a severely debilitating disorder with a suspected lifetime prevalence of 0.7% and an average age of onset between 16 and 30 years (Zheng et al., 2018


The genius of the LR3 modificationsubstituting an Arginine for a Glutamic Acid at the third position and adding a 13 amino acid extension peptideis that it dramatically reduces its affinity for these binding proteins

The citrus flavonone naringenin reduces lipopolysaccharide-induced inflammatory pain and leukocyte recruitment by inhibiting NF-B activation
