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Autonomic nervous system dysfunction (ANSD) is a relevant contributor to some of the clinical features in RTT patients that leads to multiple impairments ranging from anxiety, GI dysfunction, breathing disturbances, peripheral vascular control alteration (19) to sleep issues (3), heart rate variability (HRV) (2022), and increased risk of sudden death (23, 24)

The muscles were minced into very small pieces using scalpels and transferred to a 5-mL glass homogenizer

Newall AR, Orser R, Hunt M
Mechanisms and regulation of endothelial VEGF receptor signalling

Clinical Phytoscience, 7 (1), 1-12
