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In a PD-related toxin model, exposure to MPP resulted in a selective reduction of BFP ( LMX1A -lineage) cells, demonstrating a higher vulnerability of DA neuron progenitors and mature DA neurons, an effect difficult to quantify without a lineage reporter 82

38 These detoxification-related proteins promote metabolic inactivation of APAP, thus protecting the liver from damage induced by NAPQI (Figure 2)

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[DOI] [PubMed] [Google Scholar] 15.Beinhardt S et al