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A deficiency can lead to fatigue, weakness, memory issues, mood changes, and, in severe cases, even nerve damage

These experts questioned the value of further hypothesis generating epidemiologic studies and stated that prospective clinical trials are urgently needed

These Phase 1 trials tested various doses administered via subcutaneous injection to determine the maximum tolerated dose and identify any dose-limiting toxicities

Mezian K, Ricci V, Mittal N, Novotn T, Chang KV, zakar L, Naka O
