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Pharmacological or gene inhibition of glutathione transporters, including multidrug resistant protein 1, can block cell GSH release, reduce intracellular ROS levels and production of oxidized phosphatidylcholine, thereby inhibiting cell ferroptosis

Continuous ROS production results in oncogene and tumor suppressor gene changes, as well as chromosomal abnormalities by oxidative genome damage, which includes the oxidation of guanine to form 8-OhdG and 8-oxo,7,8-dihydroguanosine (8-OHG) in RNA and DNA (100)

May be unrelated to shot, but one day after shot I began to have pain on the top of my left eye

The current sate of knowledge has moved on in 30 odd years and yet B12 maintenance dose has since worsened

DOI:10.1016/j.abb.2023.109699 13