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Description
Unfortunately, as there is no clear guidance, consideration on a patient-by-patient basis is required

Because of their high metabolic activity, the adrenal glands, which are required for the production of steroid hormones that regulate different physiological processes, are vulnerable to oxidative damage ( 4 Oxidative stresses Oxidative stress occurs when prooxidant molecules like ROS and reactive nitrogen species (RNS) get produced in excess when antioxidant systems are not working efficiently ( When ROS levels exceed the antioxidant defences of the body, they can damage lipids, proteins, and DNA

It also inhibits melanin production, helping to lighten hyperpigmentation and brighten the skin tone

Tongbin Chen, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Ambrose 2016)