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In a study of children with acute lymphoblastic leukemia (ALL) receiving maintenance chemotherapy, milk thistle extract standardized to 33% silybinin was given at a daily dose of 80 mg to 320 mg of silybinin (approximately 5.1 mg/kg/day)

Gentile S, Strollo F, Guarino G, et al

In humans, ochratoxin A can have a severe immunosuppressive effect at low and high exposure doses

Consequently, PDA@Pt as a potent modulator of inflammatory responses, presenting novel avenues for anti-inflammatory treatments in nanomedicine

& Zifeng, P
