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Brevilin A attenuates cartilage destruction in osteoarthritis mouse model by inhibiting inflammation and ferroptosis via SIRT1/Nrf2/GPX4 signaling pathway

Therefore, rational drug compatibility should be guided by both functional synergy and quantitative monitoring, while also considering individual differences and classical contraindications to ensure safety and efficacy

High-hydrostatic-pressure extraction and ultrasound-assisted methods, while promising, require substantial capital investment and energy optimisation for commercial viability

According to 2022 data, primary liver cancer (comprising HCC and intrahepatic cholangiocarcinoma) ranked as the sixth most frequently diagnosed cancer worldwide, and the third leading cause of cancer-related deaths after lung and colorectal cancers [75]

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