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Levodopa monotherapy produced drowsiness in the first round of 131 PD patients and restricted the dosage of levodopa in 14% of patients (Lesser et al., 1979)

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It is naturally produced in the body through exposure to sunlight and can also be obtained through certain foods and supplementation

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Establishing this foundational knowledge is the first and most critical step in ensuring that any development program for either entity is built upon accurate chemical data, a clear understanding of mechanistic action, and strict adherence to the specific compliance and safety protocols governing research substances
