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J Neurol Neurosurg Psychiatry 76(8):10461057

As described in the following sections or the detailed review by Hervouet et al
It has its own unique morphological, biochemical, and genetic features
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However, in neurodegenerative conditions, impaired mitochondrial function leads to increased ROS generation and a diminished capacity to neutralize them, resulting in the accumulation of ROS and elevated oxidative stress within brain cells [67,68,87]
