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Central to this dysfunction is impaired mitochondrial oxidative phosphorylation, which significantly reduces adenosine triphosphate (ATP) production, consequently impairing cardiac contractility 4,5,6
Blockade of SOCE protects HT22 cells from hydrogen peroxide-induced apoptosis

& Lotery, A

11:a035048
Despite the wealth of evidence that characterizes the metabolically unfavorable changes in hepatic pathways linked to estrogen deficiency (8, 13), the potential for estrogen-based hormone replacement therapy (HRT) to limit the development of MASLD has not been rigorously tested
