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Description
Specifically, TGF-1 induced a 3.2-fold increase in -sma mRNA and a two-fold increase in col11, while Gepon elicited more modest increases of 1.6- and 1.4-fold, respectively

Other documented adverse effects include decreased appetite (which contributes to the therapeutic effect), fatigue, injection site reactions, dizziness, and modest increases in heart rate (typically 2-4 beats per minute)

10.1126/science.adx0043 86 ShiC.ZhangJ.WangH.ChenC.HanM.GaoL.et al (2023)

Psychiatry Investig 17:616626

Mechanism of Action: How Tesamorelin and Sermorelin Work Tesamorelin Tesamorelin binds directly to GHRH receptors in the anterior pituitary, powerfully triggering GH secretion