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Because the milligram amount is fixed, a lighter body gets more drug exposure per pound: roughly 22% more at 70 kg and about a third less at 120 kg, compared with a 90 kg reference. The dose still comes from response and tolerability, but a lighter person is running a hotter exposure at the same number on the vial

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Tebib J, Mariette X, Bourgeois P, Flipo R-M, Gaudin P, Le Lot X, Gineste P, Guy L, Mansfield CD, Moussy A, et al

Before the situation got worse, the army could escort us to Juba but now it is not clear whose army is in charge
