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Description
Strengths and Limitations Strengths: Rigorous double-blind, placebo-controlled design Use of validated outcome measures Low dropout rate Demonstrated feasibility and safety Limitations: Small sample size (n=34) Limited generalizability High placebo effect, common in FMS research Short follow-up duration (only 4 weeks post-treatment) Context in FMS Treatment Current pharmacological options for FMS include NSAIDs, tramadol, pregabalin, and antidepressants, but these often have modest efficacy and undesirable side effects

J Life Sci Appl Res 4(2):8895 Berardesca E, Cameli N (2021) Vitamin E supplementation in inflammatory skin diseases

Its an important amino acid in the body but as a supplement, L-lysine may provide similar benefits

Prior to its exploration in IBD, the regulatory role of miRNAs in ferroptosis was extensively mapped in oncology and ischemic injury [73,74,75,76,77,78]

Medication may also be beneficial
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