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Description
These results are interesting, but almost all of them come from studies on rats and mice not people

Most products were tested from single vials

Animal studies show that mice prone to obesity have high NNMT levels in their white fat tissue

Yu YM, So SKC, Khallouq BB

The most comprehensive review to date, published in JAAOS Global Research & Reviews , reached the same conclusion: Although preclinical studies are promising, there is a current lack of clinical trials (Rahman et al., 2026)